Researchers from the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) brought forward the potential of high doses of a specific adjuvant molecule, namely CpG oligonucleotide, in successfully modulating the immune system’s allergic response to the main cat allergen Fel d 1, thereby inducing a tolerance-promoting reaction and reverting the main […]

Asthma afflicts more than 300 million people worldwide. The most severe manifestation, known as non-Th2, or non-atopic childhood asthma, represents the majority of the cases, greater than 85%, particularly in low-income countries, according to Hyunok Choi, an associate professor at the Lehigh University College of Health. Yet, whether non-Th2 is a distinct disease (or endotype) […]

In a small study, researchers found college athletes who contracted COVID-19 rarely had cardiac complications. Most had mild COVID symptoms that did not require treatment, and in a small percentage of those with abnormal cardiac testing, there was no evidence of heart damage on special imaging tests. All athletes returned to sports without any health […]

Ernest Shackleton Researchers from Massachusetts General Hospital (MGH) appear to have solved the 120-year-old mystery surrounding the failing health of famed Antarctic explorer Sir Ernest Shackleton over the course of his daring expeditions to Antarctica in the early part of the twentieth century. In a paper published online in the Journal of Medical Biography, the […]

Thin and brittle bones are strongly linked to women’s heart disease risk, with thinning of the lower (lumbar) spine, top of the thigh bone (femoral neck), and hip especially predictive of a heightened heart attack and stroke risk, suggests research in the journal Heart. Osteoporosis, often dubbed brittle bone disease, is common, particularly among women […]

As the COVID-19 pandemic has progressed, it has become clear that many survivors — even those who had mild cases — continue to manage a variety of health problems long after the initial infection should have resolved. In what is believed to be the largest comprehensive study of long COVID-19 to date, researchers at Washington […]

The first large study showing that leisure time physical activity and occupational physical activity have opposite, and independent, associations with cardiovascular disease risk and longevity is published today in European Heart Journal, a journal of the European Society of Cardiology (ESC). “We adjusted for multiple factors in our analysis, indicating that the relationships were not […]

A mental health hospital has been placed in special measures after a number of patients died with Covid-19.Several whistleblowers came forward with concerns about The John Munroe Hospital in Leek, Staffordshire, the Care Quality Commission (CQC) said.Inspectors found poor infection control measures in place both there and at its second hospital, the Edith Shaw.The John […]

University of Queensland researchers have confirmed a link between depression and stomach ulcers, in the world’s largest study of genetic factors in peptic ulcer disease.Professor Naomi Wray from UQ’s Institute for Molecular Bioscience (IMB) and Queensland Brain Institute and and Dr Yeda Wu from IMB have provided clues to how the gut and brain work […]

Boys who regularly play video games at age 11 are less likely to develop depressive symptoms three years later, finds a new study led by a UCL researcher.The study, published in Psychological Medicine, also found that girls who spend more time on social media appear to develop more depressive symptoms. Taken together, the findings demonstrate […]

Scientists at Sanford Burnham Prebys have identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes COVID-19. Knowing which genes help control viral infection can greatly assist researchers’ understanding of factors that affect disease severity and also suggest possible therapeutic options. The genes in question are related to interferons, the body’s […]

A new study from the University of California, Irvine shows that compounds in both green and black tea relax blood vessels by activating ion channel proteins in the blood vessel wall. The discovery helps explain the antihypertensive properties of tea and could lead to the design of new blood pressure-lowering medications. Published in Cellular Physiology […]

Drinking plenty of both green tea and coffee is linked to a lower risk of dying from any cause among people with type 2 diabetes, suggests research published in the online journal BMJ Open Diabetes Research & Care.Drinking 4 or more daily cups of green tea plus 2 or more of coffee was associated with […]

Loneliness is a risk factor associated with adolescents being drawn into compulsive internet use. The risk of compulsive use has grown in the coronavirus pandemic: loneliness has become increasingly prevalent among adolescents, who spend longer and longer periods of time online. A study investigating detrimental internet use by adolescents involved a total of 1,750 Finnish […]

Despite deaths and hospitalisations linked to many new psychoactive substances (NPS), an international wastewater study led by the University of South Australia shows just how prevalent ‘party pills’ and ‘bath salts’ are in different parts of the world. In a new paper published in Water Research, the world’s most comprehensive wastewater analysis of NPS shows […]

A new study out of the University of Chicago Medicine following young adult drinkers for 10 years has found that individuals who reported the highest sensitivity to alcohol’s pleasurable and rewarding effects at the start of the trial were more likely to develop an alcohol use disorder (AUD) over the course of the study. Moreover, […]

In the hours after we die, certain cells in the human brain are still active. Some cells even increase their activity and grow to gargantuan proportions, according to new research from the University of Illinois Chicago. In a newly published study in the journal Scientific Reports, the UIC researchers analyzed gene expression in fresh brain […]

A new concept of on-demand drug delivery system has emerged in which the drugs are automatically released from in vivo medical devices simply by shining light on the skin. A research team led by Professor Sei Kwang Hahn of the Department of Materials Science and Engineering and Professor Kilwon Cho of the Department of Chemical […]

Melanoma is by far the deadliest form of skin cancer, killing more than 7,000 people in the United States in 2019 alone. Early detection of the disease dramatically reduces the risk of death and the costs of treatment, but widespread melanoma screening is not currently feasible. There are about 12,000 practicing dermatologists in the US, […]

A pain-free, organic and biodegradable drug delivery patch may be on the horizon for home health care patients soon. Researchers from Tohoku University have developed a biobattery-powered device capable of both delivering large molecule pharmaceuticals across the skin barrier and extracting interstitial fluid for diagnostic purposes. They published their approach online in Nature Communications. The […]

A new study is the first to identify how human brains grow much larger, with three times as many neurons, compared with chimpanzee and gorilla brains. The study, led by researchers at the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge, UK, identified a key molecular switch that can make ape brain organoids […]

Using molecular dating tools and epidemiological simulations, researchers at University of California San Diego School of Medicine, with colleagues at the University of Arizona and Illumina, Inc., estimate that the SARS-CoV-2 virus was likely circulating undetected for at most two months before the first human cases of COVID-19 were described in Wuhan, China in late-December […]